Order Information
Catalog# Size Price
P20350 100μl $280
 
Specification
Entrez Gene ID 5265
Aliases PI; A1A; AAT; PI1; A1AT; SERPINA1
Clone# 2B12
MW 47kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human AAT expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide
 
Application
WB 1/500 - 1/2000
IHC N/A
ICC N/A
FCM N/A
ELISA Propose dilution 1/10000
Description
AAT, also known as SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1. It is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Severe Serpin A1 deficiency leads to several clinical complications such as pulmonary emphysema, juvenile hepatisis, cirrhosis and hepatocellular carcinoma.
 
References
1. J Proteome Res. 2005 Nov-Dec;4(6):2070-80.
2. Neuro Endocrinol Lett. 2008 Aug;29(4):482-4.