Order Information
Catalog# Size Price
P20375 100μl $280
 
Specification
Entrez Gene ID 3170
Aliases HNF3B; TCF3B; MGC19807
Clone# 7H4B7
MW 48kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of FOXA2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
 
Application
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ICC N/A
FCM N/A
ELISA Propose dilution 1/10000
Description
FOXA2 (forkhead box A2), also known as HNF3B (hepatocyte nuclear factor 3, beta). It is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for FOXA2.
 
References
1. Hepatology. 2008 Aug;48(2):597-606.
2. Cancer Res. 2004 Jun 15;64(12):4137-47.