Order Information
Catalog# Size Price
P30108 100μl $280
 
Specification
Entrez Gene ID 2670
Aliases FLJ45472; GFAP
Clone# 6A6
MW 50kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human GFAP expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
 
Application
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ICC 1/200 - 1/1000
FCM N/A
ELISA Propose dilution 1/10000
Description
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.Tissue specificity: Expressed in cells lacking fibronectin.ABCAM:It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves.In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
 
References
1. Acta Neuropathol. 2009 Jun;117(6):667-75.
2. Schizophr Res. 2009 Jul;112(1-3):54-64.