Order Information
Catalog# Size Price
P20271 100μl $320
 
Specification
Entrez Gene ID 79727
Aliases CSDD1; LIN-28; LIN28A; ZCCHC1
Clone# 6D1F9
MW 23kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of LIN28 (aa93-209) expressed in E. Coli.
Formulation Antibody are purified by protein G affinity chromatography. Liquid in 0.01M Phosphate buffer, pH 7.4 containing 0.03% sodium azide.
 
Application
WB 1/500 - 1/2000
IHC N/A
ICC 1/200 - 1/1000
FCM N/A
ELISA Propose dilution 1/10000
Description
LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation.
 
References
1. Dev Dyn. 2005 Feb;232(2):487-97.
2. Mol Cell Biol. 2005 Nov;25(21):9198-208.