Order Information
Catalog# Size Price
P30119 100μl $280
 
Specification
Entrez Gene ID 20674
Aliases lcc; ysb; Sox-2; Sox2
Clone# 10F10
MW 34kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human SOX2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
 
Application
WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ICC 1/200 - 1/1000
FCM N/A
ELISA Propose dilution 1/10000
Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
 
References
1. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401.
2. J Biol Chem. 2008 Nov 28;283(48):33730-5.
3. Nature. 2008 Oct 23;455(7216):1124-8.