Order Information
Catalog# Size Price
P30361 100μl $310
 
Specification
Entrez Gene ID 7139
Aliases CMH2; RCM3; TnTC; cTnT; CMPD2; LVNC6
Clone# 1G1
MW 36kDa
Host/Isotype Mouse IgG1
Storage 4℃; -20℃ for long term storage
Species Reactivity Human
Immunogen Purified recombinant fragment of human troponin T2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
 
Application
WB 1/500 - 1/2000
IHC N/A
ICC N/A
FCM 1/200 - 1/400
ELISA Propose dilution 1/10000
Description
The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
 
References
Cardiovasc Res. 2010 Jun 1;86(3):452-60.
Circ Cardiovasc Genet. 2009 Aug;2(4):306-13.