Knockout Cell Lines


Samples from patients with rare diseases, such as neurological diseases, are often limited. To overcome this issue, induced pluripotent stem cells (iPSCs) represent an almost limitless cell source, and thus provide an excellent opportunity to generate disease models for rare diseases and to validate new therapeutic approaches. They have become an important tool for studying genetic diseases like Krabbe disease and muscular dystrophy. They’re also used in studying cancer, diabetes, Alzheimer’s and many other well-known disorders that can be linked to genetics, but only develop under certain circumstances.
With the aid of gene knockout technology, genetic researchers have not only made significant breakthroughs in understanding the onset of certain diseases, but in treating them as well. iPSCs help avoid the need to use human subjects in studies that would normally be dangerous or unethical. Moreover, with the help of knockout studies, researchers are better able to understand the function of genes as they relate to each other. As a result, the use of a single or multiple gene knockout can often lead to unparalleled discoveries that would normally be difficult to attain.
We at Alstem developed a series of gene knockout lines in our human iPSCs. These ALSTEM human iPS cell lines are good candidates for studying disease pathogenesis, and related pathologies, as well as providing a platform for drug discovery.
Restrictions: Alstem iPS Cell Lines and iPS cell-derived lines are subject to a Material Transfer Agreement and User Notice. Contact Us
Product List
ID | Catalog# | Name | Unit | Unit Price (USD) | Actions |
---|---|---|---|---|---|
237 | iPS21 | ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
239 | iPS41 | PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
238 | iPS31 | LRP1 Knockout Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
241 | iPS51 | KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
242 | iPS61 | AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
243 | iPS71 | LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF) | 5x105 cells/vial | $2,835.00 | Add to Cart |
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